BDBM702882 US20240360157, Example 236::cyclopropyl(3-(2-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone

SMILES Cn1cc(-c2cc3c(N4CC5CCC(C4)N5C(=O)C4C[C@H]4F)ncnc3[nH]2)cn1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 702882   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandPNGBDBM702882(cyclopropyl(3-(2-(1-methyl-1H-pyrazol-4-yl)-1H-pyr...)
Affinity DataIC50: 3.80nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Biogen Ma

US Patent
LigandPNGBDBM702882(cyclopropyl(3-(2-(1-methyl-1H-pyrazol-4-yl)-1H-pyr...)
Affinity DataIC50: 145nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Biogen Ma

US Patent
LigandPNGBDBM702882(cyclopropyl(3-(2-(1-methyl-1H-pyrazol-4-yl)-1H-pyr...)
Affinity DataIC50: 99nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase JAK3 [3-974](Human)
Biogen Ma

US Patent
LigandPNGBDBM702882(cyclopropyl(3-(2-(1-methyl-1H-pyrazol-4-yl)-1H-pyr...)
Affinity DataIC50: 253nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent