BDBM702758 US20240360157, Example 112

SMILES O=C([C@@H]1C[C@H]1F)N1C2CCC1CN(c1ccnn3cc(-c4ccnc(C(F)(F)F)c4)cc13)C2

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 702758   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandPNGBDBM702758(US20240360157, Example 112)
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Biogen Ma

US Patent
LigandPNGBDBM702758(US20240360157, Example 112)
Affinity DataIC50: 37nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Biogen Ma

US Patent
LigandPNGBDBM702758(US20240360157, Example 112)
Affinity DataIC50: 38nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [3-974](Human)
Biogen Ma

US Patent
LigandPNGBDBM702758(US20240360157, Example 112)
Affinity DataIC50: 835nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
Go to US Patent