BDBM702734 ((1S,2R)-2-fluorocyclopropyl)(3-(6-(2-methoxypyridin-4-yl)pyrrolo[1,2-b]pyridazin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone::US20240360157, Example 88

SMILES COc1cc(-c2cc3c(N4CC5CCC(C4)N5C(=O)[C@@H]4C[C@H]4F)ccnn3c2)ccn1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 702734   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandPNGBDBM702734(((1S,2R)-2-fluorocyclopropyl)(3-(6-(2-methoxypyrid...)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Biogen Ma

US Patent
LigandPNGBDBM702734(((1S,2R)-2-fluorocyclopropyl)(3-(6-(2-methoxypyrid...)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Biogen Ma

US Patent
LigandPNGBDBM702734(((1S,2R)-2-fluorocyclopropyl)(3-(6-(2-methoxypyrid...)
Affinity DataIC50: 46nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase JAK3 [3-974](Human)
Biogen Ma

US Patent
LigandPNGBDBM702734(((1S,2R)-2-fluorocyclopropyl)(3-(6-(2-methoxypyrid...)
Affinity DataIC50: 604nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent