BDBM702667 US20240360157, Example 21

SMILES O=C([C@@H]1CC1(F)F)N1C2CCC1CN(c1ccnn3cc(-c4cnn(C(F)F)c4)cc13)C2

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 702667   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandPNGBDBM702667(US20240360157, Example 21)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Biogen Ma

US Patent
LigandPNGBDBM702667(US20240360157, Example 21)
Affinity DataIC50: 39nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Biogen Ma

US Patent
LigandPNGBDBM702667(US20240360157, Example 21)
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [3-974](Human)
Biogen Ma

US Patent
LigandPNGBDBM702667(US20240360157, Example 21)
Affinity DataIC50: 565nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
Go to US Patent