BDBM702002 US12129258, Example 9

SMILES C[C@H]1COC(=O)c2cnn3ccc(nc23)N[C@H](C)c2cc(F)ccc2S1

InChI Key InChIKey=GDVDELGPSHNWGV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 702002   

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM702002(US12129258, Example 9)
Affinity DataIC50: 0.540nMAssay Description:The compound powder was dissolved in 100% DMSO (Sigma, Cat. D8418-1l) to prepare a 10 mM storage solution. The compounds had an initial test concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
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TargetHigh affinity nerve growth factor receptor(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM702002(US12129258, Example 9)
Affinity DataIC50: 0.590nMAssay Description:Based on HTRF of Cisbio (Cisbio, Cat. 08-52) principle, TRKA and ALK-L1196M kinase activity detection platform were established to determine the inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
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TargetNT-3 growth factor receptor(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM702002(US12129258, Example 9)
Affinity DataIC50: 0.760nMAssay Description:The compound powder was dissolved in 100% DMSO (Sigma, Cat. D8418-1l) to prepare a 10 mM storage solution. The compounds had an initial test concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
Go to US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM702002(US12129258, Example 9)
Affinity DataIC50: 0.860nMAssay Description:The compound powder was dissolved in 100% DMSO (Sigma, Cat. D8418-1l) to prepare a 10 mM storage solution. The compounds had an initial test concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
Go to US Patent