BDBM700911 N-(2-((2-((5-amino-4-((2- (dimethylamino)ethyl)(methyl) amino)-2-methoxyphenyl)amino)-5- chloropyrimidin-4- yl)amino)phenyl)methane- sulfonamide::US20240343694, Example 38
SMILES COc1cc(N(C)CCN(C)C)c(N)cc1Nc3ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n3
InChI Key InChIKey=TYZVQDKPFGAICT-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 700911
TargetEpidermal growth factor receptor [1-18,20-1210](Human)
Korea Reserarch Institute of Chemical Technology
US Patent
Korea Reserarch Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The activity of the compounds of the present invention against EGFR mutant enzymes was measured using the HTRF system purchased from Cisbio as follow...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-763,'FHEA',764-1210](Human)
Korea Reserarch Institute of Chemical Technology
US Patent
Korea Reserarch Institute of Chemical Technology
US Patent
Affinity DataIC50: 2nMAssay Description:The activity of the compounds of the present invention against EGFR mutant enzymes was measured using the HTRF system purchased from Cisbio as follow...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Human)
Korea Reserarch Institute of Chemical Technology
US Patent
Korea Reserarch Institute of Chemical Technology
US Patent
Affinity DataIC50: 14nMAssay Description:The activity of the compounds of the present invention against HER mutant enzymes was measured using the HTRF system purchased by Cisbio as follows. ...More data for this Ligand-Target Pair