BDBM700897 N-(2-((2-chloro-5-methylpyrimidin- 4-yl)amino) phenyl)methanesulfonamide::US20240343694, Example 24

SMILES Cc1cnc(Cl)nc1Nc1ccccc1CS(C)(=O)=O

InChI Key InChIKey=COXSKIBDPNDINN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 700897   

TargetEpidermal growth factor receptor [1-18,20-1210](Human)
KOREA RESERARCH INSTITUTE OF CHEMICAL TECHNOLOGY; INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

US Patent
LigandPNGBDBM700897(N-(2-((2-chloro-5-methylpyrimidin- 4-yl)amino) phe...)
Affinity DataIC50: 1nMAssay Description:The activity of the compounds of the present invention against EGFR mutant enzymes was measured using the HTRF system purchased from Cisbio as follow...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-763,'FHEA',764-1210](Human)
KOREA RESERARCH INSTITUTE OF CHEMICAL TECHNOLOGY; INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

US Patent
LigandPNGBDBM700897(N-(2-((2-chloro-5-methylpyrimidin- 4-yl)amino) phe...)
Affinity DataIC50: 3nMAssay Description:The activity of the compounds of the present invention against EGFR mutant enzymes was measured using the HTRF system purchased from Cisbio as follow...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Human)
KOREA RESERARCH INSTITUTE OF CHEMICAL TECHNOLOGY; INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

US Patent
LigandPNGBDBM700897(N-(2-((2-chloro-5-methylpyrimidin- 4-yl)amino) phe...)
Affinity DataIC50: 27nMAssay Description:The activity of the compounds of the present invention against HER mutant enzymes was measured using the HTRF system purchased by Cisbio as follows. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent