BDBM700894 N-(2-((2-chloro-5-fluoropyrimidin- 4-yl)amino)phenyl)propan-1- sulfonamide::US20240343694, Example 21
SMILES CCCS(=O)(=O)Nc1ccccc1Nc2nc(Cl)ncc2F
InChI Key InChIKey=CEYBHHFUTQKZFU-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 700894
TargetEpidermal growth factor receptor [1-18,20-1210](Human)
Korea Reserarch Institute of Chemical Technology
US Patent
Korea Reserarch Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The activity of the compounds of the present invention against EGFR mutant enzymes was measured using the HTRF system purchased from Cisbio as follow...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-763,'FHEA',764-1210](Human)
Korea Reserarch Institute of Chemical Technology
US Patent
Korea Reserarch Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:The activity of the compounds of the present invention against EGFR mutant enzymes was measured using the HTRF system purchased from Cisbio as follow...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Human)
Korea Reserarch Institute of Chemical Technology
US Patent
Korea Reserarch Institute of Chemical Technology
US Patent
Affinity DataIC50: 46nMAssay Description:The activity of the compounds of the present invention against HER mutant enzymes was measured using the HTRF system purchased by Cisbio as follows. ...More data for this Ligand-Target Pair