BDBM700878 US20240343694, Example 5::tert-butyl (4-((2- (dimethylamino)ethyl)(methyl) amino)-2-methoxy-5- nitrophenyl)carbamate
SMILES COc1cc(N(C)CCN(C)C)c([N+](=O)[O-])cc1NC(=O)OC(C)(C)C
InChI Key InChIKey=GPEOSDIKTVSDHN-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 700878
TargetEpidermal growth factor receptor [1-18,20-1210](Human)
Korea Reserarch Institute of Chemical Technology
US Patent
Korea Reserarch Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The activity of the compounds of the present invention against EGFR mutant enzymes was measured using the HTRF system purchased from Cisbio as follow...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetEpidermal growth factor receptor [1-763,'FHEA',764-1210](Human)
Korea Reserarch Institute of Chemical Technology
US Patent
Korea Reserarch Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The activity of the compounds of the present invention against EGFR mutant enzymes was measured using the HTRF system purchased from Cisbio as follow...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Human)
Korea Reserarch Institute of Chemical Technology
US Patent
Korea Reserarch Institute of Chemical Technology
US Patent
Affinity DataIC50: 34nMAssay Description:The activity of the compounds of the present invention against HER mutant enzymes was measured using the HTRF system purchased by Cisbio as follows. ...More data for this Ligand-Target Pair
Ligand InfoSimilars