BDBM700384 US20240336593, Example 147

SMILES O[C@@H]1CN(CCC1N1CCc2ccccc2C1)C(=O)c1cc(NCC(F)F)nc(n1)-n1ccnc1

InChI Key InChIKey=MAKYORZITVDIFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700384   

TargetProtein arginine N-methyltransferase 5(Human)
lnnovStoneTherapeutics Limited

US Patent
LigandPNGBDBM700384(US20240336593, Example 147)
Affinity DataIC50: 100nMAssay Description:Test method: A 1× enzyme reaction buffer (10 mM Tris 8.0 (Sigma, Cat. No. T2694-1L), 0.01% Tween-20 (Sigma, Cat. No. P2287-100 ML), 1 mM DTT (Sigma, ...More data for this Ligand-Target Pair
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US Patent