BDBM700282 2-[[4-[4-(4-Pyridyl)-1H-pyrazol-3-yl]phenoxy]methyl]quinoline-3-carboxylic acid::US20240336591, Example 29

SMILES OC(=O)c1cc2ccccc2nc1COc1ccc(cc1)-c1n[nH]cc1-c1ccncc1

InChI Key InChIKey=WRHJTIHVZZCZMK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700282   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform 2(Human)
Benevolentai Cambridge

US Patent

LigandBDBM700282(2-[[4-[4-(4-Pyridyl)-1H-pyrazol-3-yl]phenoxy]methy...)Copy SMILESCopy InChI

Affinity DataIC50: 0.100nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/10/2025
Entry Details
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