BDBM699462 (S)-N-((4-(1,2-Dihydroxyethyl)-1-(4- (trifluoromethoxy)phenyl)-1H- pyrazolo[3,4-b]pyridin-3- yl)methyl)cyclobut-1-enecarboxamide::US12110276, Compound 156

SMILES OC[C@@H](O)c1ccnc2n(nc(CNC(=O)C3=CCC3)c12)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=UKVLFZYWLKTJHR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 699462   

TargetTranscriptional enhancer factor TEF-1(Human)
Genentech

US Patent
LigandPNGBDBM699462((S)-N-((4-(1,2-Dihydroxyethyl)-1-(4- (trifluoromet...)
Affinity DataIC50: 33nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTranscriptional enhancer factor TEF-4(Human)
Genentech

US Patent
LigandPNGBDBM699462((S)-N-((4-(1,2-Dihydroxyethyl)-1-(4- (trifluoromet...)
Affinity DataIC50: 25nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Genentech

US Patent
LigandPNGBDBM699462((S)-N-((4-(1,2-Dihydroxyethyl)-1-(4- (trifluoromet...)
Affinity DataIC50: 740nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTranscriptional enhancer factor TEF-3(Human)
Genentech

US Patent
LigandPNGBDBM699462((S)-N-((4-(1,2-Dihydroxyethyl)-1-(4- (trifluoromet...)
Affinity DataIC50: 7.80nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In DepthDetails
US Patent