BDBM699324 N-methyl-N-((1-(4- (trifluoromethoxy)phenyl)-1H-indazol- 3-yl)methyl)acrylamide::US12110276, Compound 18

SMILES CN(Cc1nn(-c2ccc(OC(F)(F)F)cc2)c2ccccc12)C(=O)C=C

InChI Key InChIKey=FCPKNDLTVJTEJO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 699324   

TargetTranscriptional enhancer factor TEF-1(Human)
Genentech

US Patent
LigandPNGBDBM699324(N-methyl-N-((1-(4- (trifluoromethoxy)phenyl)-1H-in...)
Affinity DataIC50: 6.80nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-4(Human)
Genentech

US Patent
LigandPNGBDBM699324(N-methyl-N-((1-(4- (trifluoromethoxy)phenyl)-1H-in...)
Affinity DataIC50: 66nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Genentech

US Patent
LigandPNGBDBM699324(N-methyl-N-((1-(4- (trifluoromethoxy)phenyl)-1H-in...)
Affinity DataIC50: 100nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-3(Human)
Genentech

US Patent
LigandPNGBDBM699324(N-methyl-N-((1-(4- (trifluoromethoxy)phenyl)-1H-in...)
Affinity DataIC50: 3.40nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent