BDBM699124 US20240327418, Example LEE37

SMILES CCCNNC(=O)c1ccc(CNC(=O)CCCCCCCNC(=O)\C=C\c2cccnc2)cc1

InChI Key InChIKey=LIXOSUQGEBHZSS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 699124   

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699124(US20240327418, Example LEE37)
Affinity DataIC50: 17.8nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699124(US20240327418, Example LEE37)
Affinity DataIC50: 84.1nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699124(US20240327418, Example LEE37)
Affinity DataIC50: 1.98nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent