BDBM699120 US20240327418, Example LEE19

SMILES CCCNNC(=O)c1ccc(CNC(=O)c2cc3cnccc3s2)cc1

InChI Key InChIKey=LMXXQTRUQMEVPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 699120   

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699120(US20240327418, Example LEE19)
Affinity DataIC50: 10.1nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699120(US20240327418, Example LEE19)
Affinity DataIC50: 60nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699120(US20240327418, Example LEE19)
Affinity DataIC50: 1.20nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699120(US20240327418, Example LEE19)
Affinity DataIC50: 1.00E+5nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent