BDBM699110 US20240327418, Example LEE13

SMILES CCCNNC(=O)c1ccc(CNC(=O)\C=C\c2ccccn2)cc1

InChI Key InChIKey=UNFDJHFGKZUZCU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 699110   

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699110(US20240327418, Example LEE13)
Affinity DataIC50: 13.2nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699110(US20240327418, Example LEE13)
Affinity DataIC50: 49.2nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699110(US20240327418, Example LEE13)
Affinity DataIC50: 1.82nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent