BDBM696512 Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12bS)-10-(4-((4-aminobenzo[d]oxazol-7-yl)methyl)phenyl)-7-hydroxy-8b-(2- hydroxyacetyl)-6a,8a-dimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2′,1′:4,5]indeno[1,2d][1,3]dioxolan-4(2H)-one ::US20240307415, Compound 007

SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Cc2ccc(N)c3ncoc23)cc1

InChI Key InChIKey=TYLNLYKVURYCPP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696512   

TargetGlucocorticoid receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696512(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50:  17.1nMAssay Description:The binding activity of the compound to GR was determined using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (brand: Thermo, Cat. No: A1589...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
1/16/2025
Entry Details
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