BDBM695769 US12084420, Compound 368a::US12084420, Compound 368b

SMILES OCCS(=O)(=O)Nc1ccc2N(C[C@]3(CC[C@]4(CC4)CC3)c2c1)C(=O)c1ccc(o1)C(O)C1CCCC1

InChI Key InChIKey=HSOANIQOYHSAQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 695769   

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM695769(US12084420, Compound 368b | US12084420, Compound 3...)
Affinity DataIC50: 3nMAssay Description:Table 9: Test compounds were plated in a 3× dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM695769(US12084420, Compound 368b | US12084420, Compound 3...)
Affinity DataIC50: 3.5nMAssay Description:Table 9: Test compounds were plated in a 3× dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
Go to US Patent