BDBM695732 US12084420, Compound 336a

SMILES CS(=O)(=O)Nc1ccc2N(C[C@]3(CC[C@@H](CC3)C(F)F)c2c1)C(=O)c1cccc(c1)S(=O)(=O)NC12CC(C1)C2

InChI Key InChIKey=QMCSBINIISTWDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695732   

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM695732(US12084420, Compound 336a)
Affinity DataIC50: 8.5nMAssay Description:Table 9: Test compounds were plated in a 3× dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
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