BDBM695557 N-(1'-(3-((4,4-difluoropiperidin-1- yl)sulfonyl)benzoyl)-4- methylspiro[cyclohexane-1,3'-indolin]- 5'-yl)methanesulfonamide::US12084420, Compound 24

SMILES CC1CCC2(CN(C(=O)c3cccc(c3)S(=O)(=O)C3CCC(F)(F)CC3)c3ccc(NS(C)(=O)=O)cc23)CC1

InChI Key InChIKey=IDKXJXXRETYRIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695557   

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM695557(US12084420, Compound 24 | N-(1'-(3-((4,4-difluorop...)
Affinity DataIC50: 10nMAssay Description:Table 9: Test compounds were plated in a 3× dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
1/6/2025
Entry Details
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