BDBM691403 US20240279174, Compound JH-LPH-33

SMILES CC(=O)N1CCc2cc(ccc12)S(=O)(=O)N1CCN(CC1)c1cc(Cl)cc(c1)C(F)(F)F

InChI Key InChIKey=PDEIRNVIXFZSSJ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 691403   

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandPNGBDBM691403(US20240279174, Compound JH-LPH-33)
Affinity DataIC50: 104nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetUDP-2,3-diacylglucosamine hydrolase()
Hoffmann-La Roche

US Patent
LigandPNGBDBM691403(US20240279174, Compound JH-LPH-33)
Affinity DataIC50: 143nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent