BDBM689323 US12053473, Example I-54

SMILES C[C@@H](Nc1nc(C)nc2cc(C)c(O[C@H]3CCN(C3)C(=O)C3CC3)cc12)c1cc(N)cc(c1)C(F)(F)F

InChI Key InChIKey=NDHIAYBMDZHWDM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689323   

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689323(US12053473, Example I-54)
Affinity DataIC50: 4nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In DepthDetails
US Patent