BDBM689094 US20240190892, Example 52

SMILES Fc1c(Cl)ccc2NC(=O)O[C@@]3(CCN(C3)c3cncc(NC(=O)Cc4ccc(Cn5ccccc5=O)cc4)c3)c12

InChI Key InChIKey=BJZFSZGJWSZYHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 689094   

TargetPlasma kallikrein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689094(US20240190892, Example 52)
Affinity DataIC50: 19nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of plasma kallikrein can be determined using a relevant purified serine prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCoagulation factor XI(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689094(US20240190892, Example 52)
Affinity DataIC50: 1.00E+4nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent