BDBM688565 US20240190854, Example 60

SMILES Cn1nc(-c2ccccc2[C@@H](N)Cc2ccccn2)c2ccccc12

InChI Key InChIKey=FNNXOTVWAPCLAI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 688565   

LigandPNGBDBM688565(US20240190854, Example 60)
Affinity DataIC50: 3.10E+3nMAssay Description:PatchXpress 7000A Solutions are used to record HCN currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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LigandPNGBDBM688565(US20240190854, Example 60)
Affinity DataIC50: 3.00E+4nMAssay Description:PatchXpress 7000A Solutions are used to record HCN currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

LigandPNGBDBM688565(US20240190854, Example 60)
Affinity DataIC50: 3.00E+4nMAssay Description:PatchXpress 7000A Solutions are used to record HCN currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
King''s College London

US Patent
LigandPNGBDBM688565(US20240190854, Example 60)
Affinity DataIC50: 320nMAssay Description:IonWorks Quattro Solutions are used to record hERG and nav1.5 currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
King''s College London

US Patent
LigandPNGBDBM688565(US20240190854, Example 60)
Affinity DataIC50: 9.20E+3nMAssay Description:IonWorks Quattro Solutions are used to record hERG and nav1.5 currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent