BDBM688521 N-(1-((2- aminopyrimidin-5- yl)methyl)indolin-6-yl)- 3-((4-methylpiperazin-1- yl)methyl)-5- (trifluoromethyl) benzamide::US20240190847, Example 21

SMILES CN1CCN(Cc2cc(cc(c2)C(F)(F)F)C(=O)Nc2ccc3CCN(Cc4cnc(N)nc4)c3c2)CC1

InChI Key InChIKey=OERQUHBWTFEALN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 688521   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688521(US20240190847, Example 21 | N-(1-((2- aminopyrimid...)
Affinity DataIC50: 65nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688521(US20240190847, Example 21 | N-(1-((2- aminopyrimid...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688521(US20240190847, Example 21 | N-(1-((2- aminopyrimid...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent