BDBM688520 1-((2-((1-(2- (dimethylamino)ethyl)-1H- pyrazol-4- yl)amino)pyrimidin-5- yl)methyl)-N-(3-((4- methylpiperazin-1- yl)methyl)-5- (trifluoromethyl)phenyl) indoline-6-carboxamide::US20240190847, Example 20

SMILES CN(C)CCn1cc(Nc2ncc(CN3CCc4ccc(cc34)C(=O)Nc3cc(CN4CCN(C)CC4)cc(c3)C(F)(F)F)cn2)cn1

InChI Key InChIKey=WWQKCUBTSUHYBO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 688520   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688520(US20240190847, Example 20 | 1-((2-((1-(2- (dimethy...)
Affinity DataIC50: 65nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688520(US20240190847, Example 20 | 1-((2-((1-(2- (dimethy...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688520(US20240190847, Example 20 | 1-((2-((1-(2- (dimethy...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent