BDBM688516 Step 1; tert-butyl 3-methyl-6-03-(trifluoromethyl)phenyl)carbamoyl)indoline-1-carboxylate (Intermediate 28)::US20240190847, Example 16

SMILES COCCn1cc(Nc2ncc(CN3CCc4ccc(cc34)C(=O)Nc3cccc(c3)C(F)(F)F)cn2)cn1

InChI Key InChIKey=IMLDCQHIIODTCI-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 688516   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688516(US20240190847, Example 16 | Step 1; tert-butyl 3-m...)
Affinity DataIC50: 10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688516(US20240190847, Example 16 | Step 1; tert-butyl 3-m...)
Affinity DataIC50: 10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688516(US20240190847, Example 16 | Step 1; tert-butyl 3-m...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688516(US20240190847, Example 16 | Step 1; tert-butyl 3-m...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent