BDBM685914 US12043645, Example 7

SMILES CCCNC(=O)[C@@H](N)CC[C@@H](CC1OC(C(O)C1O)n1cnc2c(N)ncnc12)Nc1ccccc1

InChI Key InChIKey=RSEKSYNJCKHLEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685914   

TargetSet1/Ash2 histone methyltransferase complex subunit ASH2(Human)
MEMORIAL SLOAN-KETTERING CANCER CENTER

US Patent
LigandPNGBDBM685914(US12043645, Example 7)
Affinity DataIC50: 20nMAssay Description:This assay relies on Whatman P-81 filter paper, which binds peptides but not SAM. Protein Methyl Transferases (PMTs) transfer 3H-Me of [3H-Me]-SAM to...More data for this Ligand-Target Pair
In DepthDetails
US Patent