BDBM684753 US20240228491, Example 30

SMILES COc1ccc(CNc2c(-c3ccco3)c(=O)n(-c3ccc(Cl)cc3)c3nc(ccc23)C(F)(F)F)c(OC)c1

InChI Key InChIKey=MGJBRPWWETZYTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684753   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM684753(US20240228491, Example 30)
Affinity DataIC50: 13.4nMAssay Description:The specific steps were as follows: The compounds having the test starling concentration of 1 uM or 10 uM were diluted into 10 concentration points i...More data for this Ligand-Target Pair
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US Patent