BDBM684673 US20240228460, Compound (102)::US20240228460, Compound (103)

SMILES Cc1cc[nH]c(=O)c1C(=O)NC[C@H](NC(=O)c1cncc2ccccc12)c1ccc2ccccc2c1

InChI Key InChIKey=LPXXPLBNKLRBRN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 684673   

TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684673(US20240228460, Compound (102) | US20240228460, Com...)
Affinity DataIC50: 1.60E+3nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
Go to US Patent

TargetProcathepsin L(Human)
Variational AI

US Patent
LigandPNGBDBM684673(US20240228460, Compound (102) | US20240228460, Com...)
Affinity DataIC50: 4.78E+4nMAssay Description:Assays to evaluate the inhibition of cathepsin L contained 25 pM cathepsin L (RD systems: 952-CY-010), 5 uM Z-LR-AMC fluorogenic peptide substrate, 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684673(US20240228460, Compound (102) | US20240228460, Com...)
Affinity DataIC50: 7.12E+4nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
Go to US Patent

TargetProcathepsin L(Human)
Variational AI

US Patent
LigandPNGBDBM684673(US20240228460, Compound (102) | US20240228460, Com...)
Affinity DataIC50: 3.68E+4nMAssay Description:Assays to evaluate the inhibition of cathepsin L contained 25 pM cathepsin L (RD systems: 952-CY-010), 5 uM Z-LR-AMC fluorogenic peptide substrate, 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
Go to US Patent