BDBM684544 US12030880, Example 9

SMILES Cc1ncccc1Oc1ccc(cc1-c1cn(C)c(=O)c2[nH]ccc12)N=S(C)(C)=O

InChI Key InChIKey=KIHBDFDDLHQERS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 684544   

TargetBromodomain-containing protein 4 [44-168](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM684544(US12030880, Example 9)
Affinity DataIC50: 3nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [349-460](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM684544(US12030880, Example 9)
Affinity DataIC50: 0.75nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD2) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent