BDBM684542 US12030880, Example 7

SMILES CCNC(=O)c1cc2c(cn(C)c(=O)c2[nH]1)-c1cc(ccc1Oc1c(C)cccc1Cl)N=S(C)(C)=O

InChI Key InChIKey=ZZPRYPIJUPXAFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 684542   

TargetBromodomain-containing protein 4 [44-168](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM684542(US12030880, Example 7)
Affinity DataIC50: 24.3nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
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TargetBromodomain-containing protein 4 [349-460](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM684542(US12030880, Example 7)
Affinity DataIC50: 0.340nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD2) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent