BDBM68378 MLS000073940::N-(3-Cyano-4,5-dimethyl-thiophen-2-yl)-2-(4-methyl-5-m-tolyloxymethyl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetamide::N-(3-cyano-4,5-dimethyl-2-thienyl)-2-[[4-methyl-5-[(3-methylphenoxy)methyl]-1,2,4-triazol-3-yl]thio]acetamide::N-(3-cyano-4,5-dimethyl-2-thiophenyl)-2-[[4-methyl-5-[(3-methylphenoxy)methyl]-1,2,4-triazol-3-yl]thio]acetamide::N-(3-cyano-4,5-dimethyl-thiophen-2-yl)-2-[[4-methyl-5-[(3-methylphenoxy)methyl]-1,2,4-triazol-3-yl]sulfanyl]ethanamide::N-(3-cyano-4,5-dimethylthiophen-2-yl)-2-[[4-methyl-5-[(3-methylphenoxy)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetamide::SMR000001996::cid_654910

SMILES Cc1sc(NC(=O)CSc2nnc(COc3cccc(C)c3)n2C)c(C#N)c1C

InChI Key InChIKey=YQGRQJRPPYUKKA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 68378   

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM68378(N-(3-cyano-4,5-dimethylthiophen-2-yl)-2-[[4-methyl...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay