BDBM682905 US20240208981, Compound 95

SMILES Cc1nc(nc(c1F)C(C)(C)O)N1C[C@@H]2CN(C[C@@H]2C1)C(=O)c1cccc(F)c1-n1nccn1

InChI Key InChIKey=HMANLMMDKBFYCO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 682905   

TargetCytochrome P450 1A2(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM682905(US20240208981, Compound 95)
Affinity DataIC50: 1.00E+5nMAssay Description:1. Experimental ObjectiveThe human liver microsome incubation system was used to rapidly predict the inhibitory effect of the compounds on CYP450 enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
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TargetCytochrome P450 2C9(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM682905(US20240208981, Compound 95)
Affinity DataIC50: 1.00E+5nMAssay Description:1. Experimental ObjectiveThe human liver microsome incubation system was used to rapidly predict the inhibitory effect of the compounds on CYP450 enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM682905(US20240208981, Compound 95)
Affinity DataIC50: 8.27E+4nMAssay Description:1. Experimental ObjectiveThe human liver microsome incubation system was used to rapidly predict the inhibitory effect of the compounds on CYP450 enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM682905(US20240208981, Compound 95)
Affinity DataIC50: 1.00E+5nMAssay Description:1. Experimental ObjectiveThe human liver microsome incubation system was used to rapidly predict the inhibitory effect of the compounds on CYP450 enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent