BDBM682802 2-cyclobutyl-7-(isoquinolin-4- yl)-5,7-diazaspiro[3.4]octane- 6,8-dione::US20240208970, Compound 1::US20240208970, Compound 2::US20240208970, Compound 3
SMILES O=C1NC2(CC(C2)C2CCC2)C(=O)N1c1cncc2ccccc12
InChI Key InChIKey=YKGOQXICHYEMJW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 682802
Affinity DataIC50: 380nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
Affinity DataKd: 141nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair