BDBM68222 Thiazolidinone core, 6

SMILES OC(=O)C(Cc1ccccc1)N1C(=S)S\C(=C\c2cccc(Br)c2)C1=O

InChI Key InChIKey=AFRNHDVVLHZGOZ-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 68222   

TargetUDP-galactopyranose mutase(Pseudomonas aeruginosa (g-Proteobacteria))
University of Wisconsin-Madison

LigandPNGBDBM68222(Thiazolidinone core, 6)
Affinity DataIC50: 1.60E+3nM Kd:  9.40E+3nMAssay Description:To access the ability of compounds to inhibit the catalytic activity of UGM, an HPLC assay was employed. Inhibition constants were determined by mon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMed
TargetUDP-galactopyranose mutase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Wisconsin-Madison

LigandPNGBDBM68222(Thiazolidinone core, 6)
Affinity DataIC50: 6.50E+4nM Kd:  1.20E+4nMAssay Description:To access the ability of compounds to inhibit the catalytic activity of UGM, an HPLC assay was employed. Inhibition constants were determined by mon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMed