BDBM681961 US20240199649, Compound 216::US20240199649, Compound 388

SMILES CNc1nc(N[C@@H]2CCN(CC2(F)F)C2COC2)nn2ccc(-c3ccc4nc(C)n(CC(F)F)c4n3)c12

InChI Key InChIKey=VTGXADFDQVWSBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 681961   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Biosplice Therapeutics

US Patent
LigandPNGBDBM681961(US20240199649, Compound 216 | US20240199649, Compo...)
Affinity DataIC50: 0.800nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Division ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
Go to US Patent

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Biosplice Therapeutics

US Patent
LigandPNGBDBM681961(US20240199649, Compound 216 | US20240199649, Compo...)
Affinity DataIC50: 4.70nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Division ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
Go to US Patent