BDBM681816 US20240199644, Compound 13

SMILES Oc1cc(-c2c(Cl)c3OC[C@@H]4[C@@H]5CC[C@H](CN4c4nc(OC[C@@]67CCCN6C[C@H](F)C7)nc(c2F)c34)N5)c2c(C#C)c(F)ccc2c1

InChI Key InChIKey=WDAKIDPTOGWLRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 681816   

LigandPNGBDBM681816(US20240199644, Compound 13)
Affinity DataIC50: 0.691nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
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