BDBM681805 US20240199644, Compound 2
SMILES CN(C)CC1(COc2nc3N4CCNC[C@@H]4COc4c(Cl)c(cc(n2)c34)-c2cc(O)cc3ccccc23)CC1
InChI Key InChIKey=SMSKVLGTUYVUIX-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 681805
TargetRAF proto-oncogene serine/threonine-protein kinase [50-132]/GTPase KRas [1-169,G12D](Human)
Jacobio Pharmaceuticals
US Patent
Jacobio Pharmaceuticals
US Patent
Affinity DataIC50: 880nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair