BDBM681805 US20240199644, Compound 2

SMILES CN(C)CC1(COc2nc3N4CCNC[C@@H]4COc4c(Cl)c(cc(n2)c34)-c2cc(O)cc3ccccc23)CC1

InChI Key InChIKey=SMSKVLGTUYVUIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 681805   

LigandPNGBDBM681805(US20240199644, Compound 2)
Affinity DataIC50: 880nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
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