BDBM681245 N-(4-((R*)-2-(2-Fluoro-4-methoxyphenyl)propyl)-6-(((R)-1-hydroxy-4-methylpentan-2-yl)amino)-1,3,5-triazin-2-yl)methanesulfonamide (Isomer 1)::US20240199558, Example 81

SMILES COc1ccc([C@H](C)Cc2nc(N[C@@H](CO)CC(C)C)nc(NS(C)(=O)=O)n2)c(F)c1

InChI Key InChIKey=KNSZYCPMEMCZOI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 681245   

TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681245(US20240199558, Example 81 | N-(4-((R*)-2-(2-Fluoro...)
Affinity DataIC50: 49nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
In DepthDetails
US Patent