BDBM680898 US20240199525, Compound BPDA5

SMILES CCCCCCCCCOc1ccc(-c2ccc(cc2)C(O)=O)c(c1)C(O)=O

InChI Key InChIKey=UKXZHAVSPXLWEX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680898   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL

LigandBDBM680898(US20240199525, Compound BPDA5)Copy SMILESCopy InChI

Affinity DataIC50: 2.97E+4nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
West Virginia University

US Patent

LigandBDBM680898(US20240199525, Compound BPDA5)Copy SMILESCopy InChI

Affinity DataIC50: 2.97E+4nMAssay Description:First, the GST fusion of the PTP domains of SHP2, SHP1, and PTP1B were produced and purified as reported by us previously.32 The reactions were perfo...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2024
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL