BDBM680881 US20240199525, Compound BPDA6

SMILES CCCCCCCCCOc1ccc(-c2ccc(CC(O)=O)cc2)c(c1)C(O)=O

InChI Key InChIKey=RNFXSRZAAHHCDB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 680881   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680881(US20240199525, Compound BPDA6)
Affinity DataIC50: 216nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
West Virginia University

US Patent
LigandPNGBDBM680881(US20240199525, Compound BPDA6)
Affinity DataIC50: 216nMAssay Description:First, the GST fusion of the PTP domains of SHP2, SHP1, and PTP1B were produced and purified as reported by us previously.32 The reactions were perfo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680881(US20240199525, Compound BPDA6)
Affinity DataIC50: 1.00E+4nMAssay Description:First, the GST fusion of the PTP domains of SHP2, SHP1, and PTP1B were produced and purified as reported by us previously.32 The reactions were perfo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
West Virginia University

US Patent
LigandPNGBDBM680881(US20240199525, Compound BPDA6)
Affinity DataIC50: 1.18E+4nMAssay Description:First, the GST fusion of the PTP domains of SHP2, SHP1, and PTP1B were produced and purified as reported by us previously.32 The reactions were perfo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 6(Human)
West Virginia University

US Patent
LigandPNGBDBM680881(US20240199525, Compound BPDA6)
Affinity DataIC50: 216nMAssay Description:First, the GST fusion of the PTP domains of SHP2, SHP1, and PTP1B were produced and purified as reported by us previously.32 The reactions were perfo...More data for this Ligand-Target Pair
In DepthDetails
US Patent