BDBM679439 5-(2-fluoro-6- hydroxy-4-((pyridin- 2- ylamino)methyl) phenyl)-1,2,5- thiadiazolidin-3-one 1,1-dioxide::US20240180886, Example 37

SMILES Oc1cc(CNc2ccccn2)cc(F)c1N1CC(=O)NS1(=O)=O

InChI Key InChIKey=JVZOENIOFSOJCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 679439   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM679439(US20240180886, Example 37 | 5-(2-fluoro-6- hydroxy...)
Affinity DataIC50: 30nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM679439(US20240180886, Example 37 | 5-(2-fluoro-6- hydroxy...)
Affinity DataIC50: 70nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
Go to US Patent