BDBM679407 5-(4-(((4,6- dimethylpyridin-2- yl)amino)methyl)-2- fluoro-6- hydroxyphenyl)-1,2,5- thiadiazolidin-3-one 1,1-dioxide::US20240180886, Example 5

SMILES Cc1cc(C)nc(NCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2)c1

InChI Key InChIKey=QFGUROCZUJFXQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 679407   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM679407(US20240180886, Example 5 | 5-(4-(((4,6- dimethylpy...)
Affinity DataIC50: 1nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM679407(US20240180886, Example 5 | 5-(4-(((4,6- dimethylpy...)
Affinity DataIC50: 1nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
Go to US Patent