BDBM677334 US20240174652, Example 9

SMILES Cc1cnc(cn1)C(=O)NC(C1COCCO1)c1nc2cc(F)c(F)cc2n1CC(F)F

InChI Key InChIKey=ZEXCKEGDSMMMOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 677334   

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677334(US20240174652, Example 9)
Affinity DataIC50: 11nMAssay Description:The in vitro activity of the compounds according to the invention may be investigated as follows:[0111]The HEK293 cell overexpressing the human metab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
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TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677334(US20240174652, Example 9)
Affinity DataIC50: 11nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent