BDBM677322 US20240174652, Example 125 in WO2019/138017

SMILES CCn1nccc1C(=O)N[C@@H]([C@H]1CC[C@H](C)CC1)c1nc2ccc(C#N)c(F)c2[nH]1

InChI Key InChIKey=ZIYNSIYYHRZPLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 677322   

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677322(US20240174652, Example 125 in WO2019/138017)
Affinity DataIC50: 5.60E+3nMAssay Description:The in vitro activity of the compounds according to the invention may be investigated as follows:[0111]The HEK293 cell overexpressing the human metab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677322(US20240174652, Example 125 in WO2019/138017)
Affinity DataIC50: 5.60E+3nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent