BDBM677207 Synthesis of N4-methyl-N2-(1-methyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-5-(trifluoromethyl)pyridine-2,4-diamine::US20240174647, Example 128

SMILES CNc1cc(Nc2nn(C)c3ncncc23)ncc1C(F)(F)F

InChI Key InChIKey=ZZFPWRWMEKVTPE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677207   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Neuron23

US Patent

LigandBDBM677207(US20240174647, Example 128 | Synthesis of N4-methy...)Copy SMILESCopy InChI

Affinity DataIC50: 25nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/5/2024
Entry Details
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