BDBM677199 Synthesis of N4-methyl-5-(trifluoromethyl)-N2-(5-vinyl-1H-indazol-6-yl)pyrimidine-2,4-diamine::US20240174647, Example 120

SMILES CNc1nc(Nc2cc3[nH]ncc3cc2C=C)ncc1C(F)(F)F

InChI Key InChIKey=GTZPHELQYSHVEB-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677199   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Neuron23

US Patent

LigandBDBM677199(US20240174647, Example 120 | Synthesis of N4-methy...)Copy SMILESCopy InChI

Affinity DataIC50: 25nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/5/2024
Entry Details
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