BDBM677112 Synthesis of N2-(1-(cyclopropylsulfonyl)-1H-indazol-4-yl)-N4-methyl-5-(trifluoromethyl)pyrimidine-2,4-diamine::US20240174647, Example 33

SMILES CNc1nc(Nc2cccc3n(ncc23)S(=O)(=O)C2CC2)ncc1C(F)(F)F

InChI Key InChIKey=BGWPFZJANUYVQT-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677112   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Neuron23

US Patent

LigandBDBM677112(US20240174647, Example 33 | Synthesis of N2-(1-(cy...)Copy SMILESCopy InChI

Affinity DataIC50: 50nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/5/2024
Entry Details
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