BDBM677095 Synthesis of 2-(6-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-indazol-1-yl)acetonitrile::US20240174647, Example 16

SMILES CNc1nc(Nc2ccc3cnn(CC#N)c3c2)ncc1C(F)(F)F

InChI Key InChIKey=ASBJLFWJEGJGPT-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677095   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Neuron23

US Patent

LigandBDBM677095(US20240174647, Example 16 | Synthesis of 2-(6-((4-...)Copy SMILESCopy InChI

Affinity DataIC50: 50nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/5/2024
Entry Details
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